Browsing SPH Scholarly Articles by Author "Clarke, Toni-Kim"

Now showing items 1-3 of 3

    • Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation 

      Min, Josine L.; Hemani, Gibran; Hannon, Eilis; Dekkers, Koen F.; Castillo-Fernandez, Juan; Luijk, René; Carnero-Montoro, Elena; Lawson, Daniel J.; Burrows, Kimberley; Suderman, Matthew; Bretherick, Andrew D.; Richardson, Tom G.; Klughammer, Johanna; Iotchkova, Valentina; Sharp, Gemma; Al Khleifat, Ahmad; Shatunov, Aleksey; Iacoangeli, Alfredo; McArdle, Wendy L.; Ho, Karen M.; Kumar, Ashish; Söderhäll, Cilla; Soriano-Tárraga, Carolina; Giralt-Steinhauer, Eva; Kazmi, Nabila; Mason, Dan; McRae, Allan F.; Corcoran, David L.; Sugden, Karen; Kasela, Silva; Cardona, Alexia; Day, Felix R.; Cugliari, Giovanni; Viberti, Clara; Guarrera, Simonetta; Lerro, Michael; Gupta, Richa; Bollepalli, Sailalitha; Mandaviya, Pooja; Zeng, Yanni; Clarke, Toni-Kim; Walker, Rosie M.; Schmoll, Vanessa; Czamara, Darina; Ruiz-Arenas, Carlos; Rezwan, Faisal I.; Marioni, Riccardo E.; Lin, Tian; Awaloff, Yvonne; Germain, Marine; Aïssi, Dylan; Zwamborn, Ramona; van Eijk, Kristel; Dekker, Annelot; van Dongen, Jenny; Hottenga, Jouke-Jan; Willemsen, Gonneke; Xu, Cheng-Jian; Barturen, Guillermo; Català-Moll, Francesc; Kerick, Martin; Wang, Carol; Melton, Phillip; Elliott, Hannah R.; Shin, Jean; Bernard, Manon; Yet, Idil; Smart, Melissa; Gorrie-Stone, Tyler; Shaw, Chris; Al Chalabi, Ammar; Ring, Susan M.; Pershagen, Göran; Melén, Erik; Jiménez-Conde, Jordi; Roquer, Jaume; Lawlor, Deborah A.; Wright, John; Martin, Nicholas G.; Montgomery, Grant W.; Moffitt, Terrie E.; Poulton, Richie; Esko, Tõnu; Milani, Lili; Metspalu, Andres; Perry, John R. B.; Ong, Ken K.; Wareham, Nicholas J.; Matullo, Giuseppe; Sacerdote, Carlotta; Panico, Salvatore; Caspi, Avshalom; Arseneault, Louise; Gagnon, France; Ollikainen, Miina; Kaprio, Jaakko; Felix, Janine F.; Rivadeneira, Fernando; Tiemeier, Henning; van IJzendoorn, Marinus H.; Uitterlinden, André G.; Jaddoe, Vincent W. V.; Haley, Chris; McIntosh, Andrew M.; Evans, Kathryn L.; Murray, Alison; Räikkönen, Katri; Lahti, Jari; Nohr, Ellen A.; Sørensen, Thorkild I. A.; Hansen, Torben; Morgen, Camilla S.; Binder, Elisabeth B.; Lucae, Susanne; Gonzalez, Juan Ramon; Bustamante, Mariona; Sunyer, Jordi; Holloway, John W.; Karmaus, Wilfried; Zhang, Hongmei; Deary, Ian J.; Wray, Naomi R.; Starr, John M.; Beekman, Marian; van Heemst, Diana; Slagboom, P. Eline; Morange, Pierre-Emmanuel; Trégouët, David-Alexandre; Veldink, Jan H.; Davies, Gareth E.; de Geus, Eco J. C.; Boomsma, Dorret I.; Vonk, Judith M.; Brunekreef, Bert; Koppelman, Gerard H.; Alarcón-Riquelme, Marta E.; Huang, Rae-Chi; Pennell, Craig E.; van Meurs, Joyce; Ikram, M. Arfan; Hughes, Alun D.; Tillin, Therese; Chaturvedi, Nish; Pausova, Zdenka; Paus, Tomas; Spector, Timothy D.; Kumari, Meena; Schalkwyk, Leonard C.; Visscher, Peter M.; Davey Smith, George; Bock, Christoph; Gaunt, Tom R.; Bell, Jordana T.; Heijmans, Bastiaan T.; Mill, Jonathan; Relton, Caroline L. (Springer Science and Business Media LLC, 2021-09)
      Characterising genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and disease. Here we describe results of DNA methylation-quantitative trait loci ...

    • KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference 

      Schumann, Gunter; Liu, Chunyu; O’Reilly, Paul; Gao, He; Song, Parkyong; Xu, Bing; Ruggeri, Barbara; Amin, Najaf; Jia, Tianye; Preis, Sarah; Lepe, Marcelo Segura; Akira, Shizuo; Barbieri, Caterina; Baumeister, Sebastian; Cauchi, Stephane; Clarke, Toni-Kim; Enroth, Stefan; Fischer, Krista; Hällfors, Jenni; Harris, Sarah; Hieber, Saskia; Hofer, Edith; Hottenga, Jouke-Jan; Åsa Johansson; Joshi, Peter; Kaartinen, Niina; Laitinen, Jaana; Lemaitre, Rozenn; Loukola, Anu; Jian’an Luan; Lyytikäinen, Leo-Pekka; Mangino, Massimo; Manichaikul, Ani; Mbarek, Hamdi; Milaneschi, Yuri; Moayyeri, Alireza; Mukamal, Kenneth; Nelson, Christopher; Nettleton, Jennifer; Partinen, Eemil; Rawal, Rajesh; Robino, Antonietta; Rose, Lynda; Sala, Cinzia; Satoh, Takashi; Schmidt, Reinhold; Schraut, Katharina; Scott, Robert; Smith, Albert Vernon; Starr, John; Teumer, Alexander; Trompet, Stella; Uitterlinden, André G.; Venturini, Cristina; Vergnaud, Anne-Claire; Verweij, Niek; Vitart, Veronique; Vuckovic, Dragana; Wedenoja, Juho; Yengo, Loic; Yu, Bing; Zhang, Weihua; Zhao, Jing Hua; Boomsma, Dorret; Chambers, John; Chasman, Daniel; Daniela, Toniolo; de Geus, Eco; Deary, Ian; Eriksson, Johan; Tõnu Esko; Eulenburg, Volker; Franco, Oscar; Froguel, Philippe; Gieger, Christian; Grabe, Hans; Gudnason, Vilmundur; Gyllensten, Ulf; Harris, Tamara; Hartikainen, Anna-Liisa; Heath, Andrew; Hocking, Lynne; Hofman, Albert; Huth, Cornelia; Jarvelin, Marjo-Riitta; Jukema, J. Wouter; Kaprio, Jaakko; Kooner, Jaspal; Kutalik, Zoltan; Lahti, Jari; Langenberg, Claudia; Lehtimäki, Terho; Liu, Yongmei; Madden, Pamela; Martin, Nicholas; Morrison, Alanna; Penninx, Brenda; Pirastu, Nicola; Psaty, Bruce; Raitakari, Olli (National Academy of Sciences, 2016)

    • Minimal Phenotyping Yields Genome-Wide Association Signals of Low Specificity for Major Depression 

      Cai, Na; Revez, Joana A.; Adams, Mark J.; Andlauer, Till F. M.; Breen, Gerome; Byrne, Enda M.; Clarke, Toni-Kim; Forstner, Andreas J.; Grabe, Hans J.; Hamilton, Steven P.; Levinson, Douglas F.; Lewis, Cathryn M.; Lewis, Glyn; Martin, Nicholas G.; Milaneschi, Yuri; Mors, Ole; Muller-Myhsok, Bertram; Penninx, Brenda W. J. H.; Perlis, Roy H.; Pistis, Giorgio; Potash, James B.; Preisig, Martin; Shi, Jianxin; Smoller, Jordan W.; Streit, Fabien; Tiemeier, Henning; Uher, Rudolf; Van der Auwera, Sandra; Viktorin, Alexander; Weissman, Myrna M.; Kendler, Kenneth S.; Flint, Jonathan (Nature Publishing Group, 2020-03-30)
      Minimal phenotyping refers to the reliance on the use of a small number of self-report items for disease case identification, increasingly used in genome-wide association studies (GWAS). Here we report differences in genetic ...