Browsing SPH Scholarly Articles by Title
Now showing items 2189-2208 of 6362
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Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot”
(Public Library of Science, 2010)We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility. We therefore used a two-stage approach ... -
Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat
(Springer Netherlands, 2015)Cadmium (Cd) is a nephrotoxic environmental pollutant that causes insidious injury to the proximal tubule that results in severe polyuria and proteinuria. Cystatin C is a low molecular weight protein that is being evaluated ... -
Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines
(BioMed Central, 2013)Background: Photocopiers emit nanoparticles with complex chemical composition. Short-term exposures to modest nanoparticle concentrations triggered upper airway inflammation and oxidative stress in healthy human volunteers ... -
Evaluation of early body shape for epidemiological research in absence of objective measurements
(BioMed Central, 2012) -
Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial
(BioMed Central, 2016)Background: Evidence has existed for decades that higher doses of rifampin may be more effective, but potentially more toxic, than standard doses used in tuberculosis treatment. Whether increased doses of rifampin could ... -
Evaluation of Old and New Tests of Heterogeneity in Epidemiologic Meta-Analysis
(Oxford University Press, 1999)The identification of heterogeneity in effects between studies is a key issue in meta-analyses of observational studies, since it is critical for determining whether it is appropriate to pool the individual results into ... -
Evaluation of stromal HGF immunoreactivity as a biomarker for melanoma response to RAF inhibitors
(2013)Of more than 150,000 published studies evaluating new biomarkers, fewer than 100 biomarkers have been implemented for patient care[1]. One reason for this is lack of rigorous testing by the medical community to validate ... -
Evaluation of the 8q24 prostate cancer risk locus and MYC expression
(American Association for Cancer Research, 2009)Polymorphisms at 8q24 are robustly associated with prostate cancer risk. The risk variants are located in nonprotein coding regions and their mechanism has not been fully elucidated. To further dissect the function of this ... -
Evaluation of the False Recent Classification Rates of Multiassay Algorithms in Estimating HIV Type 1 Subtype C Incidence
(Mary Ann Liebert Inc, 2014)Laboratory cross-sectional assays are useful for the estimation of HIV incidence, but are known to misclassify individuals with long-standing infection as recently infected. The false recent rate (FRR) varies widely across ... -
An evaluation of the FDA's analysis of the costs and benefits of the graphic warning label regulation
(BMJ Publishing Group, 2015)The Family Smoking Prevention and Tobacco Control Act of 2009 gave the Food and Drug Administration (FDA) regulatory authority over cigarettes and smokeless tobacco products and authorised it to assert jurisdiction over ... -
Evaluation of the first year of the Oxpal Medlink: A web-based partnership designed to address specific challenges facing medical education in the occupied Palestinian territories
(SAGE Publications, 2014)Objectives: To (1) evaluate educational needs of clinical students at Al-Quds University Medical School in the West Bank; (2) address these needs where possible using synchronous distance learning, with clinicians in Oxford ... -
Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics
(American Society of Microbiology, 2015)ABSTRACT Until recently, Ebola virus (EBOV) was a rarely encountered human pathogen that caused disease among small populations with extraordinarily high lethality. At the end of 2013, EBOV initiated an unprecedented disease ... -
Evaluation of the Public Health Impacts of Traffic Congestion: A Health Risk Assessment
(BioMed Central, 2010)Background: Traffic congestion is a significant issue in urban areas in the United States and around the world. Previous analyses have estimated the economic costs of congestion, related to fuel and time wasted, but few ... -
Evaluation of the UNREST questionnaire for testing the social resistance framework
(, 2013)Background The recently developed social resistance framework addresses a widespread pattern whereby non-dominant minority groups, such as ethnic/racial minorities and people of low socioeconomic status, often engage in ... -
Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk
(Nature Publishing Group, 2011)Background: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor ... -
Event Rates, Hospital Utilization, and Costs Associated with Major Complications of Diabetes: A Multicountry Comparative Analysis
(Public Library of Science, 2010)Philip Clarke and colleagues examined patient-level data for over 11,000 participants with type 2 diabetes from 20 countries and find that major complications of diabetes significantly increased hospital use and costs ... -
Event-related potentials to repeated speech in 9-month-old infants at risk for autism spectrum disorder
(BioMed Central, 2014)Background: Atypical neural responses to repeated auditory and linguistic stimuli have been reported both in individuals with autism spectrum disorder (ASD) and their first-degree relatives. Recent work suggests that the ... -
Every Body Counts: Measuring Mortality From the COVID-19 Pandemic
(American College of Physicians, 2020-09-11)As of mid-August 2020, more than 170 000 U.S. residents have died of coronavirus disease 2019 (COVID-19); however, the true number of deaths resulting from COVID-19, both directly and indirectly, is likely to be much higher. ... -
Evidence for a Secular Trend in Age of Menarche
(New England Journal of Medicine (NEJM/MMS), 1982) -
Evidence for a U-Shaped Relationship Between Prehospital Vitamin D Status and Mortality: A Cohort Study
(Oxford University Press, 2014)Objective: The objective of the study was to examine the association between prehospital serum 25-hydroxyvitamin D [25(OH)D] and the risk of mortality after hospital admission. Design: We performed a retrospective cohort ...