Browsing SPH Scholarly Articles by Title
Now showing items 370-389 of 6362
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Antioxidative enzyme activities in human erythrocytes.
(American Association for Clinical Chemistry, 1997)Reliable and standardized methods are necessary to determine the expression of antioxidative enzymes and their role in maintaining health. In addition, the variability of the enzyme activities within the general population ... -
Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection
(Public Library of Science, 2010)Background: Human immunodeficiency virus (HIV) infection that persists despite antiretroviral therapy (ART) is a daunting problem. Given the limited evidence that resting CD4+ T cell infection (RCI) is affected by the ... -
Antiretroviral pre-exposure prophylaxis implementation in the United States: a work in progress
(International AIDS Society, 2015)Introduction: After the initial approval of the use of tenofovir disoproxil fumarate-emtricitabine (TDF/FTC) by the US Food and Drug Administration in 2012 for anti-HIV pre-exposure prophylaxis (PrEP), uptake was initially ... -
Antiretroviral Regimen and Suboptimal Medication Adherence Are Associated With Low-Level Human Immunodeficiency Virus Viremia
(Oxford University Press, 2015)Episodes of human immunodeficiency virus low-level viremia (LLV) are common in the clinical setting, but its association with antiretroviral therapy (ART) regimen and adherence remains unclear. Antiretroviral therapy ... -
Antiretroviral Regimens in Pregnancy and Breast-Feeding in Botswana
(New England Journal of Medicine (NEJM/MMS), 2010)BACKGROUND: The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy during breast-feeding are ... -
Antiretroviral Therapy in Relation to Birth Outcomes among HIV-infected Women: A Cohort Study
(Oxford University Press, 2016)Although the beneficial effects of antiretroviral (ARV) therapy for preventing mother-to-child transmission are indisputable, studies in developed and developing countries have reported conflicting findings on the association ... -
Antiretroviral Therapy to Prevent HIV Acquisition in Serodiscordant Couples in a Hyperendemic Community in Rural South Africa
(Oxford University Press, 2016)Background. Antiretroviral therapy (ART) was highly efficacious in preventing human immunodeficiency virus (HIV) transmission in stable serodiscordant couples in the HPTN-052 study, a resource-intensive randomized controlled ... -
Antiviral Combination Therapy with Interferon/Peginterferon Plus Ribavirin for Patients with Chronic Hepatitis C in Germany: A Health Technology Assessment Commissioned by the German Agency for Health Technology Assessment
(German Medical Science, 2003)Objective: The purpose of this health technology assessment (HTA), commissioned by the German Agency for HTA at the German Federal Ministry of Health and Social Security, was to systematically review the evidence on ... -
Antiviral Resistance and the Control of Pandemic Influenza
(Public Library of Science, 2007)Background: The response to the next influenza pandemic will likely include extensive use of antiviral drugs (mainly oseltamivir), combined with other transmission-reducing measures. Animal and in vitro studies suggest ... -
Aphrodisiac Use Associated with HIV Infection in Elderly Male Clients of Low-Cost Commercial Sex Venues in Guangxi, China: A Matched Case-Control Study
(Public Library of Science, 2014)Background: Rising HIV infection rates have been observed among elderly people in Guangxi, China. Inexpensive aphrodisiacs are available for purchase in suburban and rural areas. This study aims to investigate the association ... -
ApoC-III and visceral adipose tissue contribute to paradoxically normal triglyceride levels in insulin-resistant African-American women
(BioMed Central, 2013)Background: African-Americans are more insulin-resistant than whites but have lower triglyceride (TG) concentrations. The metabolic basis for this is unknown. Our goal was to determine in a cross-sectional study the effect ... -
Apolipoprotein B and non-high density lipoprotein cholesterol and the risk of coronary heart disease in Chinese
(American Society for Biochemistry and Molecular Biology, 2007)The aim of our study was to compare apolipoprotein B ( apoB), non-high density lipoprotein cholesterol ( nonHDL-C), low density lipoprotein cholesterol ( LDL-C), and other lipid markers as predictors of coronary heart ... -
Apolipoprotein C-III as a Potential Modulator of the Association Between HDL-Cholesterol and Incident Coronary Heart Disease
(Blackwell Publishing Ltd, 2012)Background: High-density lipoproteins (HDL) are structurally and metabolically heterogeneous and subclasses with differential effects on coronary heart disease (CHD) might exist. Apolipoprotein (apo) C-III, a small ... -
Apolipoprotein E in VLDL and LDL With Apolipoprotein C‐III is Associated With a Lower Risk of Coronary Heart Disease
(Blackwell Publishing Ltd, 2013)Background: Low‐density lipoprotein (LDL) with apolipoprotein C‐III (apoC‐III) is the lipoprotein species that most strongly predicts initial and recurring coronary heart disease (CHD) events in several cohorts. Thus, a ... -
Application of a New Statistical Model for Measurement Error to the Evaluation of Dietary Self-report Instruments
(Lippincott, Williams & Wilkins, 2015)Most statistical methods that adjust analyses for dietary measurement error treat an individual's usual intake as a fixed quantity. However, usual intake, if defined as average intake over a few months, varies over time. ... -
Application of a Novel Score Test for Genetic Association Incorporating Gene-Gene Interaction Suggests Functionality for Prostate Cancer Susceptibility Regions
(Karger Publishers, 2011)Aims: We introduce an innovative multilocus test for disease association. It is an extension of an existing score test that gains power over alternative methods by incorporating a parsimonious one-degree-of-freedom model ... -
Application of a Repeat-Measure Biomarker Measurement Error Model to 2 Validation Studies: Examination of the Effect of Within-Person Variation in Biomarker Measurements
(Oxford University Press, 2011)Repeat-biomarker measurement error models accounting for systematic correlated within-person error can be used to estimate the correlation coefficient (rho) and deattenuation factor (lambda), used in measurement error ... -
Application of Computational Systems Biology to Explore Environmental Toxicity Hazards
(National Institute of Environmental Health Sciences, 2011)Background: Computer-based modeling is part of a new approach to predictive toxicology. Objectives: We investigated the usefulness of an integrated computational systems biology approach in a case study involving the isomers ... -
An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation
(BioMed Central, 2004)Background: To examine interactions among the angiotensin converting enzyme (ACE) insertion/deletion, plasminogen activator inhibitor-1 (PAI-1) 4G/5G, and tissue plasminogen activator (t-PA) insertion/deletion gene ... -
Application of hair-mercury analysis to determine the impact of a seafood advisory
(Elsevier BV, 2005)Following an official recommendation in the Faroe Islands that women should abstain from eating mercury-contaminated pilot whale meat, a survey was carried out to obtain information on dietary habits and hair samples for ...