Browsing FAS Theses and Dissertations by Author "Dingus, John Grether"
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Engineering Nanobody Intracellular Behavior Through Framework Mutagenesis
Dingus, John Grether (2021-09-08)Antibodies and their derived fragments have traditionally been used to probe, neutralize, or interrogate primarily extracellular targets in living systems. While efforts have been taken to adapt the antigen-binding portions ...