Browsing FAS Theses and Dissertations by Title
Now showing items 1356-1375 of 6138
-
Drugs That Thwart Antibiotic Resistance
(2015-05-20)Antibiotics are often credited with being one of the major forces behind the expansion of human life expectancy in the past 60 years. Yet at the root of this advancement lies its potential undoing: using antibiotics promotes ... -
DTI PhantomMaker: A 3D-Printed DTI Calibration Phantom for Water Diffusion Direction and Anisotropy in the Brain
(2017-11-27)As diagnostic tools, MRI scanners performing Diffusion Tensor Imaging (DTI) require calibration to ensure standardization. This thesis presents a custom-designed 3D printer used to manufacture a novel type of DTI phantom, ... -
Du Fu: Poet Historian, Poet Sage
(2016-05-17)This dissertation argues that Du Fu’s (712-770) ascent to the pinnacle of the Chinese literary pantheon was bound up with a revolution in the ways poetry was understood to be a serious endeavor. In Du Fu’s time, poetry had ... -
Dual Antibody Functionalized Polyvinyl Alcohol and Alginate Hydrogels for Synergistic Endothelial Cell Adhesion
(2012-07-27)Motivated by the need to design minimally-invasive treatments for wide-necked cerebral aneurysms, we used computational modeling to assess aneurysm hemodynamics, examined in vitro cellular responses arising from mechanical ... -
Dual Language Learners in Transition from Home to School: The Role of Parental Attitudes and Home Language Practices in Bilingual Development
(2021-05-10)The language skills that children acquire in early childhood are essential for social relationships and school learning. For the large and growing number of children in the United States who are learning a minority language ... -
Dual Targeting of Angiopoietin-2 and VEGF Signaling for the Treatment of Glioblastoma
(2015-01-29)Glioblastoma (GBM) is the most common and aggressive brain tumor in humans. Because GBM is highly angiogenic, the anti-vascular endothelial growth factor (VEGF) antibody bevacizumab has now become the standard of care for ... -
Duration of Recovery and Susceptibility to Criticism-Induced Information-Processing Biases in Major Depression
(2013-02-22)Major depression is a highly prevalent disorder that affects millions of individuals worldwide each year. Theorists such as Aaron T. Beck (1967; 1976) revolutionized how depression is understood by proposing that cognitive ... -
Dust in Large Optical Surveys
(2012-08-03)We present results studying the distribution and properties of the diffuse dust in the Milky Way Galaxy using large optical surveys—specifically, the Sloan Digital Sky Survey (SDSS) and the Panoramic Survey Telescope and ... -
Duties of Rescue: a Moderate Account
(2013-10-18)This dissertation clarifies a challenge present in Peter Singer's famine-relief argument and offers a new account of our moral duties of rescue. The challenge, in essence, is to differentiate two classes of idealized ... -
Dürer Endures: The Prospective Aspect of a Drawing on Blue Paper
(2023-05-10)In the autumn of 1506, Albrecht Dürer drew two young faces on blue paper. 92 years later, in 1598, Aegidius Sadeler II, a talented engraver hailing from Antwerp and living in Prague, set out the very same drawing (now split ... -
Dwarfing expectations: The rapid expansion of the transiting brown dwarf population in the era of the TESS mission
(2021-05-13)This thesis presents an analysis of transiting brown dwarf (BD) systems and examines their effectiveness as tests to substellar evolutionary models. The radius, mass, and age of transiting BD systems are the parameters ... -
Dying of Encouragement: From Pitch to Production in Hollywood
(2013-10-08)Social scientists have long held that the media has a profound effect on modern societies. However, the cultural production of motion pictures and television shows has largely been neglected as a topic of inquiry. The ... -
Dynamic Collision-Free Motion Planning for Robotic Manipulation using Graphs of Convex Sets
(2023-05-12)Enabling robots to generates physically feasible and collision-frees trajectories is a fundamental problem in robotics. Current solutions take one of two approaches, using sampling based motion planners to probabilistically ... -
Dynamic dopaminergic activity controls the timing of self-timed movement.
(2021-05-14)What makes us move? Human movement disorders like Parkinson’s disease have long suggested a vital role for dopamine in movement initiation, but there exists surprisingly little evidence connecting endogenous dopaminergic ... -
Dynamic Electrochemical Processes at Solid-solid Interfaces in Alkaline Ion Batteries
(2024-01-22)This dissertation presents the theoretical, experimental and computational results of studies on the dynamic electrochemical processes at solid-solid interfaces in lithium solid state batteries and in layered sodium ... -
Dynamic expression of pleiotropic developmental genes during Drosophila embryogenesis
(2024-01-29)During embryonic development transcription must be precisely regulated over space and time to differentiate tissues and form organs. Organogenesis is directed by a set of pleiotropic transcription factors that are conserved ... -
Dynamic Hybrid Materials: Hydrogel Actuators and Catalytic Microsystems
(2013-09-30)Dynamic materials which can sense changes in their surroundings and subsequently respond or adapt by autonomously altering their functionality, surface chemistry, transparency, color, wetting behavior, adhesiveness, shape, ... -
Dynamic regulation of histone lysine methylation via the ubiquitin-proteasome system.
(2013-10-18)Lysine methylation is an important post-translational modification found on histones that is added and removed by histone lysine methyltransferases and demethylases, respectively. Lysine methylation occurs in a specific ... -
Dynamic Reorganization of Neuronal Activity Patterns in Parietal Cortex
(2017-09-08)Neuronal representations change as associations are learned between sensory stimuli and behavioral actions. However, it is poorly understood whether representations of learned associations stabilize or continue to change ... -
Dynamics and architecture of Bacillus subtilis cell division
(2022-01-11)Cells generate more cells. This proliferation requires multiple cellular-scale morphological changes from one generation to the next. One cell must physically separate into two daughters in cytokinesis. In bacteria, this ...