Browsing FAS Theses and Dissertations by Title
Now showing items 926-945 of 6138
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Controlling Cell Fate During Directed Differentiation of Human Beta Cells
(2023-06-01)Human beta cells derived from pluripotent stem cells have the potential to cure type 1 diabetes. Considerable progress has been made in differentiating insulin-secreting beta cells that can rescue animal models of diabetes, ... -
Controlling Compliance: Robotic Finger Design with Variable Stiffness for Deflections from the Target Position
(2023-06-30)In dexterous robotics, the available actuators are largely sorted into rigid or compliant actuators, which are characterized by strong or gentle grasps and by precise or simple controls, respectively. This division limits ... -
Controlling fluxes for microbial metabolic engineering
(2014-10-21)This thesis presents novel synthetic biology tools and design principles usable for microbial metabolic engineering. Controlling metabolic fluxes is essential for biological manufacturing of fuels, materials, and high value ... -
Controlling Gas Absorption in Liquids through Manipulation of Free Volume
(2023-03-14)The capture, storage, and transport of gases by liquids is integral to many biological, environmental, and industrial processes. The density of gas molecules dissolved within a liquid in equilibrium with a bulk gas phase ... -
Controlling the Supramolecular Assembly and Photophysical Properties of Atomically Precise Metal Chalcogenide and Noble Metal Nanoclusters
(2024-03-12)Noble metals such as gold and silver—when confined to the nanoscale (1–100 nm)—enable control of electromagnetic fields in the sub-wavelength size regime. This property has pioneered state-of-the-art technologies spanning ... -
Convergent Excitatory Pathways Mediate the Zebrafish Escape Behavior
(2015-05-14)Scientists have long been fascinated by how anatomical structures in the brain can generate the diversity of behaviors apparent in the animal kingdom. While the ultimate goal of neuroscience is to understand complex brain ... -
Convergent Interactions Among Pitcher Plant Microcosms in North America and Southeast Asia
(2016-08-03)Ecosystems are composed of diverse suites of organisms whose interactions are mediated by both the biotic and abiotic constraints of their environments. The complexity of ecosystems makes them both resilient and difficult ... -
Converging in Crisis: The International Impact of Europe’s Energy Crisis on Natural Gas Prices
(2023-06-30)In the span of seven years, the United States has switched from being a net importer of LNG to the largest LNG exporter in the world. This is a historic shift in energy markets that has received little attention in the ... -
CONVERSATIONAL CUES, INTERPERSONAL JUDGEMENTS, AND THE DECISION TO SPEAK
(2023-05-11)What matters more: what a person says, or how they say it? Words (verbal content) are the carriers of meaning and define conversations. But how someone says something, including facial expressions and body language (nonverbal ... -
The Conversion of the World in the Early Republic: Race, Gender, and Imperialism in the Early American Foreign Mission Movement
(2012-12-19)This is a transnational history of the early republic that focuses on religious actors. The early American foreign mission movement was an outward-looking expression of the benevolent network of the early republic. Building ... -
The Convexity of Quadratic Maps and the Controllability of Coupled Systems
(2013-09-16)A quadratic form on \(\mathbb{R}^n\) is a map of the form \(x \mapsto x^T M x\), where M is a symmetric \(n \times n\) matrix. A quadratic map from \(\mathbb{R}^n\) to \(\mathbb{R}^m\) is a map, all m of whose components ... -
Cooking in Space: Food Systems and Technologies for Long-Duration Space Travel
(2024-01-29)The question of how to feed humans in space has persisted since the beginning of space exploration. Tubes of food paste, dehydrated meals, freeze-dried packets, powdered drink pouches: space food has always needed to be ... -
Cooling, Collisions and non-Sticking of Polyatomic Molecules in a Cryogenic Buffer Gas Cell
(2014-10-21)We cool and study trans-Stilbene, Nile Red and Benzonitrile in a cryogenic (7K) cell filled with low density helium buffer gas. No molecule-helium cluster formation is observed, indicating limited atom-molecule sticking ... -
Cooperative Asymmetric Catalysis with Squaramide H-Bond Donors and Lewis Acids
(2016-07-28)A new mode of cooperative catalysis with chiral squaramide hydrogen-bond donors and trialkylsilyl trifluoromethanesulfonates (triflates) for asymmetric nucleophilic additions to oxocarbenium ions was explored. Evidence is ... -
Cooperative Binding of Sir Proteins to Nucleosomes and Its Implications for Silent Chromatin Assembly in Saccharomyces Cerevisiae
(2015-05-17)Silent chromatin, or heterochromatin, refers to regions of the genome in which genes are constitutively repressed. These regions are important for regulating developmental genes and for maintaining genome stability, and ... -
Cooperative Redox Chemistry Utilizing Bioinspired Dipyrrin Pacman Complexes
(2021-07-12)Polynuclear active sites are a common motif employed by enzymes to facilitate cooperative redox chemistry. For instance, diiron enzymes serve a variety of purposes in nature, including the promotion of C–H functionalization ... -
Cooperativity, Fluctuations and Inhomogeneities in Soft Matter
(2013-09-30)This thesis presents four investigations into mechanical aspects of soft thin structures, focusing on the effects of stochastic and thermal fluctuations and of material inhomogeneities. First, we study the self-organization ... -
Coordinate control of virulence gene expression in Francisella tularensis
(2015-05-19)Francisella tularensis is a Gram-negative, intracellular pathogen and the causative agent of tularemia. Due to its low infectious dose, ability to cause potentially fatal disease, and ability to be easily aerosolized, ... -
Coordinated Resource Management in Networked Embedded Systems
(2012-11-06)This dissertation shows that with simple programming abstractions, network-wide resource coordination is efficient and useful for programming embedded sensor networks. Existing systems have focused primarily on managing ... -
Coordination Chemistry and Electronic Structure of Iron Clusters
(2015-05-18)Mixed valence compounds have been recognized over the past five decades as a unique class of chemical species. Their distinctive spectral, electrochemical, physical and magnetic properties arise from electron delocalization ...