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Succi, Sauro

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Succi

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Sauro

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Succi, Sauro
Author's Publications: search.filters.isAuthorOfPublication.2e706479-db9a-492b-97e4-175d2da4e2da

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    Hydrokinetic Approach to Large-Scale Cardiovascular Blood Flow
    (Elsevier, 2010) Melchionna, Simone; Bernaschi, Massimo; Succi, Sauro; Kaxiras, Efthimios; Rybicki, Frank John; Mitsouras, Dimitris; Coskun, Ahmet U.; Feldman, Charles Lawrence
    We present a computational method for commodity hardware-based clinical cardiovascular diagnosis based on accurate simulation of cardiovascular blood flow. Our approach leverages the flexibility of the Lattice Boltzmann method to implementation on high-performance, commodity hardware, such as Graphical Processing Units. We developed the procedure for the analysis of real-life cardiovascular blood flow case studies, namely, anatomic data acquisition, geometry and mesh generation, flow simulation and data analysis and visualization. We demonstrate the usefulness of our computational tool through a set of large-scale simulations of the flow patterns associated with the arterial tree of a patient which involves two hundred million computational cells. The simulations show evidence of a very rich and heterogeneous endothelial shear stress pattern (ESS), a quantity of recognized key relevance to the localization and progression of major cardiovascular diseases, such as atherosclerosis, and set the stage for future studies involving pulsatile flows.
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    A Flexible High-Performance Lattice Boltzmann GPU Code for the Simulations of Fluid Flows in Complex Geometries
    (Wiley-Blackwell, 2010) Bernaschi, Massimo; Fatica, Massimiliano; Melchionna, Simone; Succi, Sauro; Kaxiras, Efthimios
    We describe the porting of the Lattice Boltzmann component of MUPHY, a multi-physics/scale simulation software, to multiple graphics processing units using the Compute Unified Device Architecture. The novelty of this work is the development of ad hoc techniques for optimizing the indirect addressing that MUPHY uses for efficient simulations of irregular domains.
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    Multiscale Simulation of Cardiovascular flows on the IBM Bluegene/P: Full Heart-Circulation System at Red-Blood Cell Resolution
    (IEEE, 2010-11) Randles, Amanda Elizabeth; Melchionna, Simone; Kaxiras, Efthimios; Lätt, Jonas; Sircar, Joy; Bernaschi, Massimo; Bison, Mauro; Succi, Sauro
    We present the first large-scale simulation of blood flow in the coronary artieries and other vessels supplying blood to the heart muscle, with a realistic description of human arterial geometry at spatial resolutions from centimeters down to 10 microns (near the size of red blood cells). This multiscale simulation resolves the fluid into a billion volume units, embedded in a bounding space of 300 billion voxels, coupled with the concurrent motion of 300 million red blood cells, which interact with one another and with the surrounding fluid. The level of detail is sufficient to describe phenomena of potential physiological and clinical significance, such as the development of atherosclerotic plaques. The simulation achieves excellent scalability on up to 294, 912 Blue Gene/P computational cores.