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Ashby, Rachel

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Ashby

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Rachel

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Ashby, Rachel

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  • Publication

    Physical activity and semen quality among men attending an infertility clinic

    (Elsevier BV, 2011) Wise, Lauren A.; Cramer, Daniel; Hornstein, Mark; Ashby, Rachel; Missmer, Stacey

    OBJECTIVE

    To examine the association between regular physical activity and semen quality.

    DESIGN

    Prospective cohort study.

    SETTING

    Couples attending one of three IVF clinics in the greater Boston area during 1993–2003. At study entry, male participants completed a questionnaire about their general health, medical history, and physical activity. Odds ratios (OR) and 95% confidence intervals (CI) were derived using generalized estimating equations models, accounting for potential confounders and multiple samples per man.

    PATIENTS

    A total of 2,261 men contributing 4,565 fresh semen samples were enrolled before undergoing their first IVF cycle.

    INTERVENTION

    None.

    MAIN OUTCOME MEASURES

    Semen volume, sperm concentration, sperm motility, sperm morphology, and total motile sperm (TMS).

    RESULTS

    Overall, none of the semen parameters was materially associated with regular exercise. Compared with no regular exercise, bicycling ≥5 hours per week was associated with low sperm concentration (OR=1.92, 95%CI=1.03–3.56) and low TMS (OR=2.05, 95%CI=1.19–3.56). These associations did not vary appreciably by age, body mass index, or history of male factor infertility.

    CONCLUSIONS

    While the present study suggests no overall association between regular physical activity and semen quality, bicycling at levels of ≥5 hours per week was associated with lower sperm concentration and TMS.