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Mellem, Kevin T

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Mellem

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Kevin T

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Mellem, Kevin T

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  • Publication

    Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis

    (Wiley-VCH Verlag Berlin, 2012) Morales, Marvin R.; Mellem, Kevin T; Myers, Andrew

    Pseudoephenamine is shown to be a versatile chiral auxiliary for asymmetric synthesis. It is free from regulatory restrictions and exhibits remarkable stereocontrol in alkylation reactions, especially those that form quaternary carbon centers. Amides derived from pseudoephenamine exhibit a high propensity to be crystalline substances and provide sharp, well-defined peaks in NMR spectra.