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Jacobs, Deborah

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Jacobs

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Deborah

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Jacobs, Deborah

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2012 - 20172

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Author's Publications: search.filters.isAuthorOfPublication.842c6a79-0dc4-4cbe-b69d-edecada0b72f

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    Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease
    (Hindawi Publishing Corporation, 2012) Le, Hong-Gam T.; Tang, Maolong; Ridges, Ryan; Huang, David; Jacobs, Deborah
    Purpose: To assess optical coherence tomography (OCT) for guiding design and fit of a prosthetic device for corneal disease. Methods: A prototype time domain OCT scanner was used to image the anterior segment of patients fitted with large diameter (18.5–20 mm) prosthetic devices for corneal disease. OCT images were processed and analyzed to characterize corneal diameter, corneal sagittal height, scleral sagittal height, scleral toricity, and alignment of device. Within-subject variance of OCT-measured parameters was evaluated. OCT-measured parameters were compared with device parameters for each eye fitted. OCT image correspondence with ocular alignment and clinical fit was assessed. Results: Six eyes in 5 patients were studied. OCT measurement of corneal diameter (coefficient of variation, CV = 0.76%), cornea sagittal height (CV = 2.06%), and scleral sagittal height (CV = 3.39%) is highly repeatable within each subject. OCT image-derived measurements reveal strong correlation between corneal sagittal height and device corneal height (r = 0.975) and modest correlation between scleral and on-eye device toricity (r = 0.581). Qualitative assessment of a fitted device on OCT montages reveals correspondence with slit lamp images and clinical assessment of fit. Conclusions: OCT imaging of the anterior segment is suitable for custom design and fit of large diameter (18.5–20 mm) prosthetic devices used in the treatment of corneal disease.
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    Diagnosis and Treatment of Ocular Pain: the Ophthalmologist’s Perspective
    (Springer US, 2017) Jacobs, Deborah
    Purpose of Review The aim of this review is to help ophthalmologists and other clinicians understand and treat ocular neuropathic pain. Recent Findings Advances in the field of neurophysiology of ocular sensations explain why some cases of dry eye may represent a pain syndrome rather than a problem related to tear status. Principles related to management of pain syndromes such as persistent post-operative pain and complex regional pain syndrome are relevant to the care of these patients. Summary Specific strategies for the ophthalmologist, including multimodal therapy comprised of local and systemic approaches, can be helpful in the care of patients with problematic ocular pain. Rather than dismiss these syndromes and these patients, ophthalmologists can serve these patients and the profession well by incorporating an understanding of ocular neuropathic pain into their practice and by collaboration in the care of patients with problematic ocular pain.