Person: Lamb, Justin
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Lamb
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Justin
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Lamb, Justin
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Publication Jet-Launching Structure Resolved Near the Supermassive Black Hole in M87(American Association for the Advancement of Science (AAAS), 2012) Doeleman, Sheperd; Fish, V. L.; Schenck, D. E.; Beaudoin, C.; Blundell, Raymond; Bower, G. C.; Broderick, Alithia Carol; Chamberlin, R.; Freund, R.; Friberg, P.; Gurwell, Mark; Ho, Po-Yi; Honma, M.; Inoue, M.; Krichbaum, T. P.; Lamb, Justin; Loeb, Abraham; Lonsdale, C.; Marrone, D. P.; Moran, James; Oyama, T.; Plambeck, R.; Primiani, Rurik; Rogers, A. E. E.; Smythe, D. L.; SooHoo, J.; Strittmatter, P.; Tilanus, R. P. J.; Titus, M.; Weintroub, Jonathan; Wright, Bennett Bennett; Young, K. H.; Ziurys, L. M.Approximately 10% of active galactic nuclei exhibit relativistic jets, which are powered by accretion of matter onto super massive black holes. While the measured width profiles of such jets on large scales agree with theories of magnetic collimation, predicted structure on accretion disk scales at the jet launch point has not been detected. We report radio interferometry observations at 1.3mm wavelength of the elliptical galaxy M87 that spatially resolve the base of the jet in this source. The derived size of 5.5 +/- 0.4 Schwarzschild radii is significantly smaller than the innermost edge of a retrograde accretion disk, suggesting that the M87 jet is powered by an accretion disk in a prograde orbit around a spinning black hole.Publication A Method for High-Throughput Gene Expression Signature Analysis(BioMed Central, 2006) Peck, David; Crawford, Emily D; Ross, Kenneth N; Stegmaier, Kimberly; Golub, Todd; Lamb, JustinGenome-wide transcriptional profiling has shown that different biologic states (for instance, disease and response to pharmacologic manipulation) can be recognized by the expression pattern of relatively small numbers of genes. However, the lack of a practical and cost-effective technology for detection of these gene expression 'signatures' in large numbers of samples has severely limited their exploitation in important medical and pharmaceutical discovery applications. Here, we describe a solution based on the combination of ligation-mediated amplification with an optically addressed microsphere and flow cytometric detection system.