Person: Bersin, Eric
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Bersin
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Eric
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Bersin, Eric
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Publication Nuclear magnetic resonance detection and spectroscopy of single proteins using quantum logic(American Association for the Advancement of Science (AAAS), 2016) Lovchinsky, Igor; Sushkov, Alexander; Urbach, Elana; de Leon, Nathalie Pulmones; Choi, Soonwon; De Greve, Kristiaan; Evans, Ruffin; Gertner, Rona; Bersin, Eric; Muller, Christopher Michael; McGuinness, L.; Jelezko, F.; Walsworth, Ronald; Park, Hongkun; Lukin, MikhailNuclear magnetic resonance spectroscopy is a powerful tool for the structural analysis of organic compounds and biomolecules but typically requires macroscopic sample quantities. We use a sensor, which consists of two quantum bits corresponding to an electronic spin and an ancillary nuclear spin, to demonstrate room temperature magnetic resonance detection and spectroscopy of multiple nuclear species within individual ubiquitin proteins attached to the diamond surface. Using quantum logic to improve readout fidelity and a surface-treatment technique to extend the spin coherence time of shallow nitrogen-vacancy centers, we demonstrate magnetic field sensitivity sufficient to detect individual proton spins within 1 second of integration. This gain in sensitivity enables high-confidence detection of individual proteins and allows us to observe spectral features that reveal information about their chemical composition.Publication NMR technique for determining the depth of shallow nitrogen-vacancy centers in diamond(American Physical Society (APS), 2016) Pham, Linh; DeVience, Stephen J.; Casola, Francesco; Lovchinsky, Igor; Sushkov, Alexander; Bersin, Eric; Lee, Junghyun; Urbach, Elana; Cappellaro, Paola; Park, Hongkun; Yacoby, Amir; Lukin, Mikhail; Walsworth, RonaldWe demonstrate a robust experimental method for determining the depth of individual shallow nitrogen-vacancy (NV) centers in diamond with ∼1 nm uncertainty. We use a confocal microscope to observe single NV centers and detect the proton nuclear magnetic resonance (NMR) signal produced by objective immersion oil, which has well understood nuclear spin properties, on the diamond surface. We determine the NV center depth by analyzing the NV NMR data using a model that describes the interaction of a single NV center with the statistically polarized proton spin bath. We repeat this procedure for a large number of individual, shallow NV centers and compare the resulting NV depths to the mean value expected from simulations of the ion implantation process used to create the NV centers, with reasonable agreement.