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Nelson, Sandra

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Nelson

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Sandra

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Nelson, Sandra
Author's Publications: search.filters.isAuthorOfPublication.e524b871-bbc3-4622-a6ae-a65e75900497

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    Outcomes According to Discharge Location for Persons Who Inject Drugs Receiving Outpatient Parenteral Antimicrobial Therapy
    (Oxford University Press, 2018) D’Couto, Helen T; Robbins, Gregory; Ard, Kevin; Wakeman, Sarah; Alves, Justin; Nelson, Sandra
    Abstract Background: Opioid use disorder poses a significant public health risk. Persons who inject drugs (PWID) suffer from high mortality and morbidity secondary to serious infectious diseases, often requiring prolonged courses of outpatient parenteral antibiotics. The goal of this study was to determine the outcomes of PWID discharged to home or to a skilled nursing or rehabilitation facility (SNF/rehab) with parenteral antibiotic treatment under an outpatient parenteral antimicrobial therapy (OPAT) program. Methods: This is a retrospective observational study. The study population was identified via hospital and OPAT databases using substance use disorder diagnoses and confirmed through chart review. The study population included hospitalized PWID with injection drug use in the preceding 2 years who were discharged between 2010 and 2015 to complete at least 2 weeks of parenteral antibiotics and monitored by the OPAT program. Retrospective chart review was used to describe patient characteristics and outcomes. Results: Fifty-two patients met inclusion criteria, 21 of whom were discharged to home and 31 were discharged to a SNF/rehab. Of the patients discharged to home, 17 (81%) completed their planned antibiotic courses without complication. Twenty (64%) patients discharged to a SNF/rehab completed the antibiotic courses without complication. Six (11%) patients had line infections, 6 (11%) had injection drug use relapse, and 12 (23%) required readmission. Conclusions: Persons who inject drugs discharged home were not more likely to have complications than those discharged to a SNF/rehab. Home OPAT may be a safe discharge option in carefully selected patients.
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    745Risk of Peripheral Blood Eosinophilia and Hypersensitivity Reactions among Patients Receiving Outpatient Parenteral Antibiotics
    (Oxford University Press, 2014) Blumenthal, Kimberly; Youngster, Ilan; Parker, Robert; Walensky, Rochelle; Nelson, Sandra
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    Percutaneous CT-guided sacroiliac joint sampling for infection: aspiration, biopsy, and technique
    (Springer Science and Business Media LLC, 2017-11-15) Knipp, David; Simeone, Frank; Nelson, Sandra; Huang, Ambrose; Chang, Connie
    Objective: To elucidate the management algorithm for sacroiliac joint sampling by percutaneous CT-guided sacroiliac joint sampling for suspected infection patients. Materials and Methods: All CT-guided sacroiliac joint sampling procedures for suspected infection were reviewed for sampling type (aspiration lavage aspiration, biopsy), microbiology results, and clinical and imaging follow-up. The gold standard was pathology. If pathology was not available, then positive blood culture with same organism as SIJ sampling, imaging and clinical follow-up, or clinical follow-up only were used. Anterior and posterior joint distention was evaluated by MRI within seven days of the procedure.