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Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications

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2010

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Wiley
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Liong, Monty, Huilin Shao, Jered B. Haun, Hakho Lee, and Ralph Weissleder. 2010. “Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications.” Advanced Materials 22 (45): 5168–72. https://doi.org/10.1002/adma.201002219.

Abstract

Highly magnetic MnFe2O4 nanocrystals (NCs) are coated with non-cross-linked carboxymethyl polyvinyl alcohol to produce conjugates that are highly stable under varying temperatures, pH, and ionic strengths. The polymer-coated NCs exhibit low nonspecific cell binding. They are also amenable to chemical linking with biomolecules, allowing for the efficient labeling of surface receptors on targeted cancer cells in vitro.

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