Publication: AIDA and UCP1 Snuggle Up to Prevent Hypothermia
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2021-03-09
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Springer Science and Business Media LLC
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Mills, Evanna L., Haopeng Xiao, and Edward T. Chouchani. “AIDA and UCP1 Snuggle up to Prevent Hypothermia.” Nature Cell Biology 23, no. 3 (March 2021): 216–18. https://doi.org/10.1038/s41556-021-00648-3.
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Abstract
In response to cold stress, mammals release norepinephrine from the sympathetic nervous system to elevate thermogenesis in brown adipose tissue (BAT) in order to maintain body temperature. This study reveals that the protein AIDA connects sympathetic input, reactive oxygen species, and uncoupling protein 1-mediated adaptive thermogenesis in BAT.
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Research Subject Categories::NATURAL SCIENCES::Biology::Cell and molecular biology::Cell biology
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