Publication: The Gain Paradox
Open/View Files
Date
2009
Authors
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Berg, Howard Curtis. 2009. The gain paradox. Progress in Biophysics and Molecular Biology 100(1-3): 2-3.
Research Data
Abstract
Chemoreceptors in Escherichia coli control the activity of a kinase that phosphorylates a response regulator that, in turn, biases the direction of rotation of flagellar motors, affecting the manner in which cells swim. A small change in receptor occupancy induces a large change in kinase activity. This gain is generated by allosteric interactions between receptors, which are arranged in clusters. The idea that such amplification might occur was advanced by [Bray et al., 1998] and [Bray, 2002].
Description
Other Available Sources
Keywords
escherichia coli, motility, chemotaxis, allostery
Terms of Use
This article is made available under the terms and conditions applicable to Open Access Policy Articles (OAP), as set forth at Terms of Service