Publication: Unraveling the Transcriptional Network Controlling ES Cell Pluripotency
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Date
2006
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Published Version
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BioMed Central
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Citation
Rao, Sridhar, and Stuart H. Orkin. 2006. Unraveling the transcriptional network controlling ES cell pluripotency. Genome Biology 7(8): 230.
Abstract
Embryonic stem cells (ES cells) are powerful tools for genetic engineering and hold significant potential for regenerative medicine. Recent work provides new insights into ES cell pluripotency and delineates separate transcriptional pathways in ES cells for maintenance of the undifferentiated state and for self-renewal.
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Keywords
STAT3, embryonic stem cells, self-renewal, mammalian embryo, differentiation, expression, induction, fusion, Oct4, Nanog
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