Publication: Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data
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Date
2007
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Centers for Disease Control and Prevention
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Pitzer, Virginia E., Sonja J. Olsen, Carl T. Bergstrom, Scott F. Dowell, and Marc Lipsitch. 2007. Little evidence for genetic susceptibility to Influenza A (H5N1) from family clustering data. Emerging Infectious Diseases 13(7): 1074-1076.
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Abstract
The apparent clustering of human cases of influenza A (H5N1) among blood relatives has been considered as evidence of genetic variation in susceptibility. We show that, by chance alone, a high proportion of clusters are expected to be limited to blood relatives when infection is a rare event.
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