Publication: Tracking the Culprit: HIV-1 Evolution and Immune Selection Revealed by Single-Genome Amplification
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Date
2009
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Rockefeller University Press
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Brumme, Zabrina L., and Bruce D. Walker. 2009. Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification. Journal of Experimental Medicine 206(6): 1215-1218.
Abstract
Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8+ T cell response and the evolution of the virus during early HIV infection.
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