Publication:

Protein knot server: detection of knots in protein structures

Thumbnail Image

Open/View Files

1933242.pdf (1.65 MB)

Date

2007

Authors

Published Version

10.1093/nar/gkm312

Journal Title

Journal ISSN

Volume Title

Publisher

Oxford University Press
The Harvard community has made this article openly available. Please share how this access benefits you.

Research Projects

Organizational Units

Journal Issue

Citation

Kolesov, Grigory, Peter Virnau, Mehran Kardar, and Leonid A. Mirny. 2007. Protein knot server: detection of knots in protein structures. Nucleic Acids Research 35: W425-W428.

Abstract

KNOTS (http://knots.mit.edu) is a web server that detects knots in protein structures. Several protein structures have been reported to contain intricate knots. The physiological role of knots and their effect on folding and evolution is an area of active research. The user submits a PDB id or uploads a 3D protein structure in PDB or mmCIF format. The current implementation of the server uses the Alexander polynomial to detect knots. The results of the analysis that are presented to the user are the location of the knot in the structure, the type of the knot and an interactive visualization of the knot. The results can also be downloaded and viewed offline. The server also maintains a regularly updated list of known knots in protein structures.

Description

Other Available Sources

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933242/pdf/

Research Data

Keywords

Terms of Use

This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service

URI

http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874789

Collections

HMS Scholarly Articles

Endorsement

Review

Supplemented By

Related Stories