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A small RNA makes a Bic difference

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2007

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BioMed Central
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Moffett, Howell F. and Carl D. Novina. 2007. A small RNA makes a Bic difference. Genome Biology 8(7): 221.

Abstract

The first highly specific knockouts of a microRNA, miR155, in mice result in multiple defects in adaptive immunity, and also show the feasibility of investigating at least some microRNAs by gene knockout.

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