Publication: A Mouse Plasma Peptide Atlas as a Resource for Disease Proteomics
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Date
2008
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BioMed Central
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Zhang, Qing, Rajasree Menon, Eric W. Deutsch, Sharon J. Pitteri, Vitor M. Faca, Hong Wang, Lisa F. Newcomb, et al. 2008. A mouse plasma peptide atlas as a resource for disease proteomics. Genome Biology 9(6): R93.
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Abstract
We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 proteins are estimated to span a 7 logarithmic range of abundance in plasma. A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis.
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