Publication: A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals
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Date
2012
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Nature Publishing Group
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Moriguchi, Hisashi, Yue Zhang, Makoto Mihara, and Chifumi Sato. 2012. A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. Scientific Reports 2: 280.
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Abstract
Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).
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