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Palladium-Mediated Fluorination of Arylboronic Acids

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2008

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Wiley
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Furuya, Takeru, Hanns Martin Kaiser, and Tobias Ritter. 2008. Palladium-mediated fluorination of arylboronic acids. Angewandte Chemie International Edition 47(32): 5993-5996.

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Abstract

Saving the best for last: Novel palladium complexes allow mild, two-step fluorination of aryl boronic acids (see scheme). The reaction is regiospecific, functional-group tolerant, has a broad substrate scope, and is ideally suited for the introduction of fluorine substituents at a late stage for aryl fluoride synthesis.

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boronic acids, fluorination, palladium, synthetic methods, tomography

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