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CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

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2011

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The Rockefeller University Press
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Kometani, Kohei, Takayuki Yamada, Yoshiteru Sasaki, Tadashi Yokosuka, Takashi Saito, Klaus Rajewsky, Masamichi Ishiai, Masaki Hikida, and Tomohiro Kurosaki. 2011. CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway. The Journal of Experimental Medicine 208(7): 1447-1457.

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CIN85 transduces B cell receptor signals to IKK-β, and its expression in B cells is essential for T cell–independent type II antibody responses in mice.

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