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Reference Group Choice and Antibiotic Resistance Outcomes

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2004

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Centers for Disease Control and Prevention
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Kaye, Keith S., John J. Engemann, Essy Mozaffari, and Yehuda Carmeli. 2004. Reference group choice and antibiotic resistance outcomes. Emerging Infectious Diseases 10(6): 1125-1128.

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Abstract

Two types of cohort studies examining patients infected with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) were contrasted, using different reference groups. Cases were compared to uninfected patients and patients infected with the corresponding, susceptible organism. VRE and MRSA were associated with adverse outcomes. The effect was greater when uninfected control patients were used.

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