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Neutrophil extracellular traps

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2013

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Landes Bioscience
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Demers, Mélanie, and Denisa D. Wagner. 2013. Neutrophil extracellular traps. Oncoimmunology 2(2): e22946.

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Abstract

Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.

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Cancer, NETs, metastasis, neutrophils, thrombosis, tumor progression

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