Publication: Ivermectin Inhibits Growth of Chlamydia trachomatis in Epithelial Cells
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Date
2012
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Public Library of Science
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Pettengill, Matthew A., Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, and David M. Ojcius. 2012. Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. PLoS ONE 7(10): e48456.
Abstract
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans. However, ivermectin has never been shown to be effective against bacterial pathogens. Here we show that ivermectin also inhibits infection of epithelial cells by the bacterial pathogen, Chlamydia trachomatis, at doses that could be envisioned clinically for sexually-transmitted or ocular infections by Chlamydia.
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Biology, Microbiology, Applied Microbiology, Medicine, Clinical Immunology, Immunity, Diagnostic Medicine, Pathology, Clinical Pathology, Clinical Microbiology, Infectious Diseases, Sexually Transmitted Diseases, Chlamydia, Zoonoses, Ocular Karva Migrans, Gynecologic Infections, Neglected Tropical Diseases, Genitourinary Infections, Ophthalmology, Eye Infections, Urology, Veterinary Science, Veterinary Microbiology, Infections Immunity, Obstetrics, Gynecology
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