Publication: Oral Immunotherapy for Food Allergy: Towards a New Horizon
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Date
2013
Published Version
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Publisher
The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
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Citation
Khoriaty, Evelyne Nassim, and Dale T. Umetsu. 2013. Oral immunotherapy for food allergy: towards a new horizon. Allergy, Asthma & Immunology Research 5(1): 3-15.
Research Data
Abstract
Food allergy has increased dramatically in prevalence over the past decade in westernized countries, and is now a major public health problem. Unfortunately for patients with food allergy, there is no effective therapy beyond food allergen avoidance, and rapid medical treatment for accidental exposures. Recently, oral immunotherapy (OIT) has been investigated as a treatment for this problem. In this review, we will discuss the progress in developing OIT for food allergy, including a novel approach utilizing Xolair (anti-IgE monoclonal antibody, omalizumab) in combination with OIT. This combination may enhance both the safety and efficacy of oral immunotherapy, and could lead to a widely available and safe therapy for food allergy.
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Keywords
Oral immunotherapy, omalizumab, anti-IgE, xolair, food allergy, desensitization
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