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Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation

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3578672.pdf (346.98 KB)

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2012

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10.1093/europace/eus380

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Oxford University Press
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Verrier, Richard L., Kapil Kumar, Tuomo Nieminen, and Luiz Belardinelli. 2012. Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation. Europace 15(3): 317-324.

Abstract

Coronary artery disease and heart failure carry concurrent risk for atrial fibrillation and life-threatening ventricular arrhythmias. We review evidence indicating that at therapeutic concentrations, ranolazine has potential for dual suppression of these arrhythmias. Mechanisms and clinical implications are discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578672/pdf/

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Ranolazine, T-wave alternans, Ventricular fibrillation, Atrial fibrillation, Sodium current

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http://nrs.harvard.edu/urn-3:HUL.InstRepos:10589790

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