Publication: Boosting leukemia-specific T cell responses in patients following stem cell transplantation
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Date
2013
Authors
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
Landes Bioscience
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Citation
Burkhardt, Ute E., and Catherine J Wu. 2013. “Boosting leukemia-specific T cell responses in patients following stem cell transplantation.” Oncoimmunology 2 (11): e26587. doi:10.4161/onci.26587. http://dx.doi.org/10.4161/onci.26587.
Research Data
Abstract
Whole tumor cell-based vaccines administered within the first 2 to 3 months after allogeneic stem cell transplantation stand out as a promising approach to enhance graft-vs.-leukemia responses. Herein, the implications of this finding for the development of strategies to improve the outcome of patients subjected to allogeneic stem cell transplantation are discussed.
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Keywords
cancer vaccines, CLL, immune reconstitution, multiepitope vaccines, neoantigens, stem cell transplantation, whole tumor-cell vaccination
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