Publication: Separation of Nanoparticles in Aqueous Multiphase Systems through Centrifugation
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Date
2012
Published Version
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American Chemical Society (ACS)
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Citation
Akbulut, Ozge, Charles R. Mace, Ramses V. Martinez, Ashok A. Kumar, Zhihong Nie, Matthew R. Patton, and George M. Whitesides. 2012. Separation of Nanoparticles in Aqueous Multiphase Systems through Centrifugation. Nano Letters 12, no. 8: 4060–4064.
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Abstract
This paper demonstrates the use of aqueous multiphase systems (MuPSs) as media for rate-zonal centrifugation to separate nanoparticles of different shapes and sizes. The properties of MuPSs do not change with time or during centrifugation; this stability facilitates sample collection after separation. A three-phase system demonstrates the separation of the reaction products (nanorods, nanospheres, and large particles) of a synthesis of gold nanorods, and enriches the nanorods from 48 to 99% in less than ten minutes using a benchtop centrifuge.
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Keywords
Centrifugation, nanoparticles, separation, polymers, multiphase systems
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