Publication: Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
Open/View Files
Date
2013
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
Landes Bioscience
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Hollon, Todd C, Richard L Price, Chang-Hyuk Kwon, and E Antonio Chiocca. 2013. “Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus.” Oncoimmunology 2 (9): e25620. doi:10.4161/onci.25620. http://dx.doi.org/10.4161/onci.25620.
Research Data
Abstract
Over the last decade, cytomegalovirus (CMV) has been suggested to promote the development of glioblastoma multiforme (GBM). Recent evidence demonstrates that CMV contributes to the progression of GBM in the context of oncosuppressor gene mutations. This finding provides further insights into the mechanisms whereby CMV exacerbates the malignancy of GBM.
Description
Other Available Sources
Keywords
viral oncology, tumor suppressor genes, brain tumor, glioma, rhabdomyosarcoma
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service