Publication: Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection
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2014-06-06
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Rothchild, Alissa Chen. 2014. Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection. Doctoral dissertation, Harvard University.
Abstract
Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg production have been identified, there are still many antimicrobial mechanisms yet to be explored. Here we characterized the role of invariant natural killer T (iNKT) cells and GM-CSF during Mtb infection.
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GM-CSF, immunology, iNKT cells, Mtb, Tuberculosis
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