Publication: Is DNA methylation of tumour suppressor genes epigenetic?
Loading...
Open/View Files
Date
2014
Authors
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
eLife Sciences Publications, Ltd
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Struhl, Kevin. 2014. “Is DNA methylation of tumour suppressor genes epigenetic?” eLife 3 (1): e02475. doi:10.7554/eLife.02475. http://dx.doi.org/10.7554/eLife.02475.
Abstract
In colorectal cancer cells, a non-epigenetic transcriptional pathway that is mediated by an oncogene maintains DNA methylation of tumour suppressor genes
Description
Other Available Sources
Research Data
Keywords
Insight, Cancer, CpG island methylator phenotype, INK4-ARF, colorectal cancer, ZNF304, KRAS, DNMT1, human, mouse
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service