Publication: Clinical Importance and Epidemiology of Quinolone Resistance
Open/View Files
Date
2014
Authors
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Kim, Eu Suk, and David C. Hooper. 2014. “Clinical Importance and Epidemiology of Quinolone Resistance.” Infection & Chemotherapy 46 (4): 226-238. doi:10.3947/ic.2014.46.4.226. http://dx.doi.org/10.3947/ic.2014.46.4.226.
Research Data
Abstract
The quinolone class of antimicrobial agents is one of most widely used classes of antimicrobial agents in outpatient and inpatient treatment. However, quinolone resistance in gram-positive and gram-negative bacteria has emerged and increased globally. This resistance limits the usefulness of quinolones in clinical practice. The review summarizes mechanisms of quinolone resistance and its epidemiology and implications in the most common clinical settings, urinary tract infections, respiratory tract infections, intraabdominal infections, skin and skin structure infections, and sexually transmitted diseases.
Description
Other Available Sources
Keywords
Quinolones, Drug resistance, Epidemiology, Mechanism, Clinical implications
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service