Publication: Successful Supercooled Liver Storage for 4 Days
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Date
2014
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Berendsen, Tim A., Bote G. Bruinsma, Catheleyne F. Puts, Nima Saeidi, O. Berk Usta, Basak E. Uygun, Maria-Louisa Izamis, Mehmet Toner, Martin L. Yarmush, and Korkut Uygun. 2014. “Successful Supercooled Liver Storage for 4 Days.” Nature medicine 20 (7): 790-793. doi:10.1038/nm.3588. http://dx.doi.org/10.1038/nm.3588.
Abstract
The realization of long–term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a novel technique based on sub–zero non–freezing tissue preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to 4 days, thereby tripling the viable preservation duration.
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