Publication: “Mouse Clone Model” for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells
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2015
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BioMed Central
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Zhang, Gang, and Yi Zhang. 2015. ““Mouse Clone Model” for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells.” Stem Cell Research & Therapy 6 (1): 255. doi:10.1186/s13287-015-0262-3. http://dx.doi.org/10.1186/s13287-015-0262-3.
Abstract
To investigate the immune-rejection and tumor-formation potentials of induced pluripotent stem cells and other stem cells, we devised a model—designated the “Mouse Clone Model”—which combined the theory of somatic animal cloning, tetraploid complementation, and induced pluripotent stem cells to demonstrate the applicability of stem cells for transplantation therapy.
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