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PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics

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2014

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American Chemical Society
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Fujimoto, Teppei, Fabian Becker, and Tobias Ritter. 2014. “PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics.” Organic Process Research & Development 18 (8): 1041-1044. doi:10.1021/op500121w. http://dx.doi.org/10.1021/op500121w.

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Abstract

We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.

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