Publication: Taking the brakes off telomerase
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Date
2015
Authors
Published Version
Journal Title
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Volume Title
Publisher
eLife Sciences Publications, Ltd
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Citation
Naxerova, Kamila, and Stephen J Elledge. 2015. “Taking the brakes off telomerase.” eLife 4 (1): e09519. doi:10.7554/eLife.09519. http://dx.doi.org/10.7554/eLife.09519.
Research Data
Abstract
Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.
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Keywords
Insight, Oncogenesis, telomerase TERT, immortalization, cancer mechanism, genome editing, tumor spectrum, ssociated systems 9 CAS9, human
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