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Status epilepticus caused by cerebral amyloid angiopathy-related inflammation

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4925902.pdf (1.14 MB)

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2016

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10.1016/j.ebcr.2016.05.003

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Elsevier
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Tolchin, Benjamin, Tadeau Fantaneanu, Michael Miller, Jeffrey Helgager, and Jong Woo Lee. 2016. “Status epilepticus caused by cerebral amyloid angiopathy-related inflammation.” Epilepsy & Behavior Case Reports 6 (1): 19-22. doi:10.1016/j.ebcr.2016.05.003. http://dx.doi.org/10.1016/j.ebcr.2016.05.003.

Abstract

This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating inflammatory process. Immunomodulatory treatment with pulse steroids resulted in rapid and dramatic clinical and radiographic improvement. Cerebral amyloid angiopathy-related inflammation should be considered in the differential diagnosis of new-onset seizures after the age of 40, when associated with fluctuating multifocal T2 hyperintensities and petechial hemorrhages on gradient echo (GRE) or susceptibility-weighted (SWI) MRI sequences.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925902/pdf/

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Cerebral amyloid angiopathy, Inflammation, Status epilepticus, MRI, EEG, Pathology

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http://nrs.harvard.edu/urn-3:HUL.InstRepos:27822327

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