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MicroRNAs in apoptosis, autophagy and necroptosis

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2015

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Impact Journals LLC
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Su, Zhenyi, Zuozhang Yang, Yongqing Xu, Yongbin Chen, and Qiang Yu. 2015. “MicroRNAs in apoptosis, autophagy and necroptosis.” Oncotarget 6 (11): 8474-8490.

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Abstract

MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for cleavage or translational repression. Numerous miRNAs regulate programmed cell death including apoptosis, autophagy and necroptosis. We summarize how miRNAs regulate apoptotic, autophagic and necroptotic pathways and cancer progression. We also discuss how miRNAs link different types of cell death.

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microRNA, apoptosis, autophagy, necroptosis, cancer progression

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