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A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis

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2016

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Oxford University Press
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Abers, Michael S., Musie S. Ghebremichael, Allison K. Timmons, H. Shaw Warren, Mark C. Poznansky, and Jatin M. Vyas. 2016. “A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis.” Open Forum Infectious Diseases 3 (1): ofw036. doi:10.1093/ofid/ofw036. http://dx.doi.org/10.1093/ofid/ofw036.

Abstract

Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA cases and occurred exclusively in hematologic patients.

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, immunosuppression, invasive aspergillosis, invasive fungal infection, neutropenia

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