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Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity

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2016

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John Wiley and Sons Inc.
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Mohebali, Donya, Jason Matos, and James Ducksoon Chang. 2016. “Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity.” Esc Heart Failure 4 (1): 71-74. doi:10.1002/ehf2.12113. http://dx.doi.org/10.1002/ehf2.12113.

Abstract

Abstract Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a multiple hit mechanism of myocyte damage that may occur following the use of multiple cardio‐toxic agents despite their administration in doses not associated with cardiotoxicity.

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Case Report, Cardiomyopathy, Cardio‐oncology, Chemotherapy

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