Publication: RNA - ligand interactions:(I) magnesium binding sites in yeast tRNA Phe
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Date
1977
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Oxford University Press (OUP)
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Holbrook, Stephen R., Joel L. Sussman, R. Wade Warrant, George Church, Sung-Hou Kim. "RNA - ligand interactions:(I) magnesium binding sites in yeast tRNA Phe." Nucleic Acids Research 4, no. 8 (1977): 2811-2820. DOI: 10.1093/nar/4.8.2811
Abstract
X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)N]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.
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Genetics
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