Life Goals Collaborative Care for Patients With Bipolar Disorder and Cardiovascular Disease Risk

Abstract

Objectives The goal of this randomized controlled pilot study was to determine whether Life Goals Collaborative Care (LGCC) compared to enhanced treatment as usual, reduced cardiometabolic factors and improved outcomes for persons with bipolar disorder from community-based practices. Methods Persons were randomized to receive LGCC (N=32) or enhanced treatment as usual (N=33). LGCC included four weekly self-management sessions and telephone contacts to encourage provider engagement and measurement-based care; enhanced treatment as usual included wellness mailings. Outcomes were body mass index-BMI, blood pressure, quality of life, functioning, and symptoms. Results Compared to enhanced treatment as usual, LGCC was not associated with reduced cardiometabolic risk factors based on 6 and 12-month repeated measures analyses. Among patients with BMI >=30 or systolic blood pressure >=140, LGCC was associated with decreased impaired functioning (respectively beta=−2.2, beta=−3.8;p=.04 for both) and depressive symptom scores (respectively beta=−2.0, beta=−3.5;both p=.04). Conclusions LGCC may improve outcomes among patients with elevated baseline cardiometabolic risk from community-based practices.