Publication: Separation and enrichment of enantiopure from racemic compounds using magnetic levitation
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Date
2014
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Royal Society of Chemistry (RSC)
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Yang, Xiaochuan, Shin Yee Wong, David K. Bwambok, Manza B. J. Atkinson, Xi Zhang, George M. Whitesides, and Allan S. Myerson. 2014. “Separation and Enrichment of Enantiopure from Racemic Compounds Using Magnetic Levitation.” Chemical Communications. doi:10.1039/c4cc02604g.
Abstract
Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products.
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