Publication: Trapping Hydrogen Sulfide (H2S) with Diselenides: The Application in the Design of Fluorescent Probes
Open/View Files
Date
2015
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
American Chemical Society
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Peng, Bo, Caihong Zhang, Eizo Marutani, Armando Pacheco, Wei Chen, Fumito Ichinose, and Ming Xian. 2015. “Trapping Hydrogen Sulfide (H2S) with Diselenides: The Application in the Design of Fluorescent Probes.” Organic Letters 17 (6): 1541-1544. doi:10.1021/acs.orglett.5b00431. http://dx.doi.org/10.1021/acs.orglett.5b00431.
Research Data
Abstract
Here we report a unique reaction between phenyl diselenide-ester substrates and H2S to form 1,2-benzothiaselenol-3-one. This reaction proceeded rapidly under mild conditions. Thiols could also react with the diselenide substrates. However, the resulted S–Se intermediate retained high reactivity toward H2S and eventually led to the same cyclized product 1,2-benzothiaselenol-3-one. Based on this reaction two fluorescent probes were developed and showed high selectivity and sensitivity for H2S. The presence of thiols was found not to interfere with the detection process.
Description
Other Available Sources
Keywords
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service