Publication: Protective inflammasome activation in AMD
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Date
2012
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Nature Publishing Group
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Chen, Jing, and Lois E H Smith. 2012. Protective Inflammasome Activation in AMD. Nat Med 18, no. 5: 658–660. doi:10.1038/nm.2761.
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Abstract
Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. AMD progression is associated with alterations in inflammatory pathways and the immune system. A new study identifies a protective role for inflammasomes in AMD, suggesting that inflammasome activation might be manipulated as a potential therapeutic strategy for this condition (pages 791-798).
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