Publication: Nevirapine Resistance in Human Immunodeficiency Virus Type 1-Positive Infants Determined Using Dried Blood Spots Stored for Up to Six Years at Room Temperature
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Date
2009
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American Society for Microbiology
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Citation
Nelson, J. A. E., A. M. Loftis, D. Kamwendo, W. W. Fawzi, T. E. Taha, R. L. Goldenberg, and S. A. Fiscus. 2009. “Nevirapine Resistance in Human Immunodeficiency Virus Type 1-Positive Infants Determined Using Dried Blood Spots Stored for Up to Six Years at Room Temperature.” Journal of Clinical Microbiology 47 (4) (February 18): 1209–1211. doi:10.1128/jcm.00254-09.
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Abstract
Dried blood spots that had been stored ambiently for 3 to 6 years lost approximately 1 log10 of human immunodeficiency virus type 1 (HIV-1) RNA, but the majority could still be genotyped for resistance. Nevirapine resistance was found in 7/16 (43.5%) HIV-1-positive HIVNET 024 infants at 4 to 6 weeks, but no resistance was found at other time points.
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